ABSTRACT
<p><b>OBJECTIVE</b>To improve the resectable rate of massive hepatic tumors and operative tolerance of hepatectomy in the treatment of advanced liver cancers.</p><p><b>METHODS</b>Sixteen cases of massive hepatic tumors were reviewed. The selective exclusion of hepatic outflow and inflow in hepatectomy was discussed.</p><p><b>RESULTS</b>All the patients had normal course after the operative procedure and no hepatic coma or other severe hepatic disturbances were observed.</p><p><b>CONCLUSION</b>While the selective exclusion of hepatic outflow and inflow were applied, the resectable rate of massive hepatic tumors and operative tolerance of hepatectomy were improved.</p>
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Carcinoma, Hepatocellular , General Surgery , Hemangioma, Cavernous , General Surgery , Hepatectomy , Methods , Hepatic Artery , General Surgery , Hepatic Veins , General Surgery , Liver Circulation , Liver Neoplasms , General SurgeryABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical manifestations, diagnosis and treatment of gastrointestinal stromal tumor (GIST).</p><p><b>METHODS</b>Clinicopathological data of 29 cases with GIST from 2003 to 2005 were retrospectively analyzed.</p><p><b>RESULTS</b>The most common clinical manifestations were abdominal pain, distention or discomfort in 16 cases (55.2%), abdominal mass in 9 (31.0%), melena and hematemesis in 5 cases (17.2%). The tumor was located in the stomach in 16 cases, the small intestine in 9, the colorectum in 2, the esophagus in one, and the duodenum in one case. All the cases underwent operation, included total gastrectomy in one case, subtotal gastrectomy in 8, partial gastrectomy in 4, local excision of the tumor in 5 cases, partial small intestine resection in 9 and right colectomy in 2 cases. The resection rate was 100% and no complication and death occurred. The positive rates of CD117(+) and CD34(+) were 93.1% and 51.7% respectively. After follow up from one to 2 years after operation, 2 cases died of tumor recurrence and metastasis, the others survived.</p><p><b>CONCLUSIONS</b>Immunohistochemical examinations of CD117 and CD34 are important diagnostic markers. Surgery is the main method of final diagnosis and treatment.</p>
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Antigens, CD34 , Metabolism , Biomarkers , Follow-Up Studies , Gastrectomy , Gastrointestinal Stromal Tumors , Diagnosis , Pathology , General Surgery , Proto-Oncogene Proteins c-kit , Metabolism , Retrospective StudiesABSTRACT
<p><b>OBJECTIVE</b>To study the anatomy of the small intestine,and investigate the optimal selection of donors,recipients,and their small intestine vessels in piglet small intestine transplantation.</p><p><b>METHODS</b>The weight and length of 30 piglets were measured. Angiography and pigments perfusion were used to observe the main vessels of the small intestine,and the length of the small intestine,and the external diameter of the main vessels of the small intestine were measured in vivo and ex vivo.</p><p><b>RESULTS</b>The length of the small intestine was 11.5 times as long as the body length, and its weight accounted for 2.3% of the body weight. The outer diameters of abdominal aorta (AT), mesenteric anterior artery (MAA) and its 5(th)-6(th) branches in vivo and ex vitro were 4.3/4.6mm, 2.5/2.7mm and 1.9/2.2mm respectively. The total number of MAA's branches was 6-8 in general and its 5(th)-6(th) branches were the longest [(20.0 +/- 7.0) mm, (22.0 +/- 8.2) mm]. The outer diameter of mesenterial anterior vein (MAV) was 1-2 mm wider than that of MAA.</p><p><b>CONCLUSIONS</b>AT, MAA and its 5(th)-6(th) branches are the preferable vessels for small intestine transplantation. In segmental small intestine transplantation, the length of the small intestine and body weight can be used to primarily select the suitable animals.</p>